Synonimes:I-Benzene,2,4-dichloro-1-methyl-;I-Toluene, 2,4-dichloro-;2,4-dichloro-1-methylbenzene;2,4-DCT;2,4-DICHLOROTOLUENE;2,4- I-DICHLOROMETHYLBENZENE;1,3-DICHLORO-4-METHYLBENZENE;2,4-dichloro-1-methyl-benzen

Inombolo ye-CAS: 95-73-8
Ifomula yemolekyuli: C7H6Cl2
Isisindo se-molecule: 161.03
Inombolo ye-EINECS: 202-445-8

Izigaba ezihlobene:imikhiqizo ejwayelekile yezolimo neyemvelo; ama-fungicides e-triazole; ama-fungicides aphakathi; izibulala-zinambuzane; izinto zokusetshenziswa eziphilayo; abaphakathi; i-organic intermediate; Izinto eziphilayo; U-Aryl; C7; I-Halogenated Hydrocarbons; I-aromatics; Amabhulokhi Okwakha; I-Chemicalbook Chemical Synthesis; I-Hydrogenated Hydrocarbons; I-OrganicBuildingBlocks;Imikhiqizo ejwayelekile ye-Analytical;Amabhulokhi wokwakha we-Organic;Izibulala-zinambuzane eziphakathi nendawo;Ama-hydrocarbon ane-halogenated;Izinto zokusetshenziswa zamakhemikhali e-organic.

2,4-Dichlorotoluene ukusetshenziswa kanye synthesis indlela
Izakhiwo zamakhemikhali: uketshezi olungenambala futhi olusobala.
Sebenzisa:
I-1) Isetshenziswa njengeziphakathi zezibulala-zinambuzane, odayi kanye nemithi, esetshenziselwa ukukhiqizwa kwe-2,4-dichlorobenzaldehyde, izidakamizwa ezifana ne-adipine, i-buprofen, njll.
2) I-2,4-I-Dichlorotoluene iyisibulala-magciwane esimaphakathi se-diniconazole ne-benzylchlorotriazole, futhi i-Chemicalbook iphinde ibe yimpahla eluhlaza yokulungisa i-2,4-dichlorobenzaldehyde.
3) Izinto zokwenziwa ze-Organic, ezisetshenziswa embonini yezemithi ukukhiqizwa kwemithi elwa nomalaleveva, i-Adepine, kanye nokuhlanganiswa kwe-ventral acid. Isetshenziswa emikhakheni yokubulala izinambuzane ukwenza i-2,4-dichlorobenzyl chloride, 2,4-dichlorobenzoyl chloride, kanye ne-2,4-dichlorobenzoic acid.

Zimbili izindlela zokwenziwa zezindlela zokukhiqiza.
1. Indlela ye-1.2,4-dichloroluene isebenzisa i-2,4-diaminotoluene njengento eluhlaza, futhi itholakala nge-diazotization kanye ne-chlorination. Faka i-hydrochloric acid namanzi ebhodweni lokuphendula, ukushisa ku-50 ℃, chaza i-2,4-diaminotoluene ngaphansi kokugqugquzela, bese ufaka i-hydrochloric acid ne-cuprous chloride ebhodweni, engeza isixazululo se-sodium nitrite engu-1% ngokulinganayo ku-Chemicalbook, Izinga lokushisa ligcinwa ku- cishe u-60 ℃, ume unganyakazi ukuze ubekwe, umkhiqizo ongahluziwe ophansi ugezwa ngamanzi uze ungathathi hlangothi, i-alkali yengezwe ku-alkali, bese igezwa ngamanzi ukuze ikhiphe i-alkali, i-2,4-dichloroluene engahluziwe iyahlukaniswa, futhi umkhiqizo oqediwe u-steam distilled. . Indlela ye-2.3-chloro-4-toluidine itholakala ngokusabela kwe-diazotization nge-sodium nitrite, nokusabela kwe-Sandmeyer nge-chloride yethusi.

2.Indlela yokukhiqiza kanye nezindlela zayo zokuyilungiselela yilezi ezilandelayo. Ngendlela ye-parachlorotoluene, i-p-chlorotoluene kanye ne-catalyst ZrCl4 kufakwa ku-reactor, bese kuthi igesi ye-chlorine ikhishwe umoya ukuze kuqhutshekwe nokusabela kwe-chlorination. Inani legesi ye-chlorine lilawulwa kuze kube sekupheleni kokusabela futhi ukusabela kuyamiswa. I-reactant etholiwe iqukethe u-85.1% we-2,4-dichloroluene. Uma i-FeCl3 isetshenziswa njenge-catalyst ukwenza ukusabela kwe-chlorination ku-10～15℃ kuze kube yilapho ukuminyana kwesixazululo kube ngu-1.025, umkhiqizo uqukethe i-2,4-dichloroluene kanye ne-3,4-dichloroluene, kanye nesilinganiso sobuningi salokhu okubili. izingxenye 100:30 . Ngemva kokuqedwa kokufakwa kwe-chlorine, geza ngamanzi ukuze ungathathi hlangothi, bese uphatha ngesisombululo se-NaOH esingu-10% ku-100～110℃ ukuze ususe okunye ukungcola. I-chloride ephathwayo iyalungiswa futhi ihlukaniswe embhoshongweni wokulungisa osebenza kahle kakhulu (2,4-dichloro Toluene bp200°C, 3,4-dichlorrotoluene bp207°C). Isivuno se-2,4-dichloroluene ne-3,4-dichloroluene sasingu-64.4% no-19.8%, ngokulandelana. Indlela ye-Ortho-chlorotoluene i-o-chlorotoluene isebenzisa i-sulfuryl chloride njenge-ejenti yokucwenga ukwenza ukusabela kwe-chlorination ku-142～196℃. Imikhiqizo yi-2,4-dichloroluene kanye ne-2,3-dichloroluene, futhi ayiphenduli Ukwakheka kwezinto ezisetshenziswayo yi-55%, 6%, kanye ne-39%, ngokulandelana. Ngemuva kokukhishwa kwe-distillation (i-2,4-dichloroluene bp 200 ° C, i-2,3-dichloroluene bp 207-208 ° C, i-o-chlorotoluene bp 157-159 ° C), i-2,4-dichloroluene yahlukaniswa. Indlela ye-Ortho-nitrotoluene I-Ortho-nitrotoluene ifakwa i-chlorine phambi kwe-FeCl3 catalyst ku-35～40℃. Lapho ukuminyana okuhlobene kwe-reactant kufinyelela ku-1.320 (15℃), geza okokusebenza kokungathathi hlangothi, futhi into esabelayo iqukethe u-15% wento eluhlaza, 2-chloro-6-nitrotoluene 49%, 4-chloro-2-nitrotoluene 21% , kanye ne-polychloride engu-15%, ngemva kokulungiswa nokwelashwa kwe-crystallization, i-Chemicalbook kuya ku-2-chloro-6-nitrotoluene Izivuno ze-4-chloro-2-nitrotoluene kanye ne-4-chloro-2-nitrotoluene zingama-50% no-30% ngokulandelanayo. I-4-chloro-2-nitrotoluene itholakala ngokusabela kokunciphisa i-hydrogenation kanye ne-steam distillation ukuthola i-4-chloro-2-amino. I-Toluene, i-diazotization kanye nokwengeza i-CH2Cl2 yokusabela kwe-Sandmeyer ukuthola i-2,4-dichlorrotoluene. Indlela isetshenziselwa ukukhiqiza i-4-chloro-2-nitrotoluene ewumkhiqizo we-2-chloro-6-nitrotoluene (esetshenziswa njengendawo emaphakathi ye-quinclorac yokubulala ukhula). I-2,4-Diaminotoluene Indlela ye-2,4-Diaminotoluene ithola ukusabela kwe-diazotization phambi kwe-NaNO2 ne-hydrochloric acid, bese yenza ukusabela kwe-Sandmeyer phambi kwe-Cu2Cl2 ukuze ithole i-2,4-dichloroluene. Indlela ye-3-Chloro-4-methylaniline 3-chloro-4-methylaniline kanye ne-hydrochloric acid yengezwa kugedlela lokusabela, isixazululo esinamanzi se-NaNO2 sengezwa ngokudonsa ngo-3～5℃, futhi ukwengeza kuqedwa kungakapheli amahora angama-2～3 ukuze kusetshenziswe i-diazotization ukusabela, uketshezi lwe-diazotized lwengezwa ngokudonsa phansi kwisisombululo se-hydrochloric acid esiqukethe i-Cu2Cl2 ku-2-5°C ukuze senze ukusabela kwe-Sandmeyer ukuze kutholwe i-2,4-dichloroluene. Phakathi kwalezi zindlela ezingenhla, i-chloride ekhiqizwa ngokusebenzisa i-p-chlorotoluene ne-o-chlorotoluene njengezisetshenziswa zokusetshenziswa iqukethe ukungcola okuningi futhi inamaphuzu abilayo afanayo. Kudingekile ukusebenzisa imibhoshongo yokulungisa esebenza kahle kakhulu ukuze ihlukaniseke ukuze uthole okungaphezu kuka-98% we-2,4-dichlorrotoluene. Lezi zindlela ezimbili zinzima ukusebenza, futhi izindleko zokutshala imishini ziphezulu. Indlela ye-2,4-diaminotoluene ayifanele ukwenziwa kwezimboni, futhi indlela ye-o-nitrotoluene kanye nendlela ye-3-chloro-4-methylaniline yokulungisa i-2,4-dichloroluene inezimiso eziyisisekelo ezifanayo, futhi zombili zidinga i-diazotization kanye ne-Sandmeyer Ekuphenduleni , kukhona ukushoda kwamanzi amaningi angcolile. Indlela ye-o-nitrotoluene isetshenziselwa ukukhiqiza ngokuhlanganyela i-2-chloro-6-nitrotoluene, ephinde yehliswe ukuze kutholwe i-2-chloro-6-aminotoluene, okuyindawo ebalulekile emaphakathi ekukhiqizweni kwe-quinclorac yokubulala ukhula.